World's First Motorcycle (1885): Daimler's "riding car"
The First Motorcycle was designed and built by the German inventors Gottlieb Daimler and Wilhelm Maybach in Bad Cannstatt (Stuttgart) in 1885. It was essentially a motorised bicycle, although the inventors called their invention the Reitwagen ("riding car"). It was also the first petroleum-powered vehicle.
World's First X-Ray (1895): Röntgen's wife hand
In 1895 Wilhelm Conrad Röntgen, professor of physics the University of Wurburg in Germany, was doing experiments with electrical discharges in evacuated glass tubes. Late in 1895 Wilhelm Röntgen was alone at night doing his experiments, this time in the dark and noticed a glow was produced on the wall, which he knew was not caused by fluorescence or visible light. He named these new, unidentified rays 'X' or if you prefer; X-rays. After several months of playing with his discovery he noticed that objects place in the path of the rays cast shadows and created images on the wall. Soon after he used a photgraphic plate and had his wife, Frau Röntgen, place her hand in the path of the X-rays, creating the world's first X-ray picture. In 1901 Wilhelm Röntgen was awarded the very first Nobel Prize in Physics for this discovery.
World's First Computer Mouse (1964): by Douglas Engelbart
The world's first computer mouse was made by Douglas Engelbart in 1964, it consisted of two gear-wheels positioned perpendicular to each other -- allowing movement on one axis. Ergonomic shape, great button placement -- and it's made of wood.
World's First Skyscraper (1885): Home Insurance Building in Chicago
Considered to be the first skyscraper in the world due to the building's unique architecture and unique weight bearing frame, the Home Insurance Building was built in 1885 in Chicago, Illinois and demolished in 1931 to make way for the Field Building (now the LaSalle National Bank Building). It was the first building to use structural steel in its frame, but the majority of its structure was composed of cast and wrought iron. It was the first tall building to be supported, both inside and outside, by a fireproof metal frame. It had 10 stories and rose to a height of 138 feet (42 m) high.
World's First Concept Car (1938): Buick Y-Job
Designed in 1938 by the famous General Motors designer Harley Earl, the Buick Y-Job is considered by most to be the first concept car. The car had power-operated hidden headlamps, "gunsight" hood ornament, wraparound bumpers, flush door handles, and prefigured styling cues used by Buick until the 1950s.